NEW Life Changing Asthma Treatment 🔎🔍
🎞️ · 14.08.2022 · 22:18:35 ··· Sonntag ⭐ 0 🎬 0
📺Vithal Panday, M.D.
🎬 · 14.08.2022 · 22:18:35 ··· Sonntag
😎 · 03.07.2024 · 15:40:29 ··· MiTTwoch
Asthma affects people of all ages. It often starts in childhood but It can develop at any age.
The good news is that New research has now found a way to treat asthma in the long term and return aiwarys to a near healthy state.
Asthma is a chronic lung condition that causes inflammation of your Airways, resulting in wheezing, breathlessness, coughing and a tight chest.
By blocking a protein involved in making airways less flexible, researchers almost completely eliminated asthmatic symptoms within 2 weeks in mice.
Treatment
Symptoms vary over over time. Allergens such as pollen, house dust mites or pet dander can worsen symptoms. The main symptoms are wheezing, breathlessness, a tight chest and coughing.
Individuals can get an asthma attack, whicrtr symptoms worsen acutely. The muscles around the airways tighten and the Airways swell, making breathing very difficult.
Bronchodilators and corticosteroids are used to treat asthma. Bronchodilators are your blue puffers, in other words salbutamol, specifically treats wheezing. Corticosteroids are your brown/orange puffers, in other words, suppresses the inflammation in the airways. These treatments work best for short term relief but not for those who have a severe disease.
Root cause: pericytes
Pericytes are a type of stem cell found in the lining of blood vessels. They are key to understanding the underlying causes of asthma.
Structural changes occur in chronic allergic asthma know as airway remodelling.
Research shows that during an asthmatic episode, pericytes moved to the airway walls. Pericytes are a type of stem cell, that have the ability to change into different tissues. Once in the airway, pericytes can develop into other types of cells, like muscles cells which make the airway less flexible.
Movement of pericytes is activated by a protein called CXCL12. LIT-927 blocked CXCL12 from working, essentially meaning that the pericytes no longer moved to the airways. Hence, LIT-927 helped reduce asthma symptoms and almost completely dissappeared within two weeks.
This novel drug would be ideally delivered in a combined formulation puffer with a long acting bronchi dilatory and a corticosteroid to suppress inflammation.
This would allow for the inflammatory and structural aspects of allergic asthma to be more effectively treated and therefore lead to an improved quality of life.
Reference: Medical News Today
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