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Novavax COVID-19 Vaccine | FDA and CDC Approved

· 29.07.2022 · 23:57:07 ··· Freitag ⭐ 0 🎬 0 📺 Vithal Panday, M.D.
Earlier this month, the FDA announced an emergency use  authorization for Novavax COVID-19 vaccine.

Research shoes Novavax to be 100% effective in preventing moderate to severe COVID-19.

Novavax uses a traditional vaccine model used previously for influenza and shingles vaccines. The United States department of health and human services has secured 3.2 million doses of Novavax for distribution in the US.

This vaccine requires two doses spaced between 3 to 8 weeks apart.

So today we will discuss

1. How is this vaccine different
2. Efficacy
3. Side effects
4. Who should/should not get the vaccine

How is this vaccine different

If we look at previous vaccines like Pfizer and modern, they utilize MRNA technology instead of using weakened or dead viral cells to teach your body how to protect itself from the live disease, the MRNA vaccines provide instructions to the body on how to creaf a spike protein. Spike proteins are also found in sars cov 2 virus cells.

The body recognises the spike protein as something foreign that it needs to defend itself from, which causes an immune response. This teaches the body how to react if ever infected by the sars cov 2 virus with the same spike proteins.

The Novavax vaccine does not use MRNA technology. It is a protein based vaccine that contains stabilised forms of the spike proteins from sars cov 2, plus an adjuvant which is a substance included in a vaccine to cause the body to have an immune response.

Novavax uses an adjuvant made from saponins that naturally occur in the bark of the Soapbark tree native to Chile.

The protein is derived from the corona virus spike protein and is formulated with Novavax's patented saponin-based matrix M adjuvant to enhance the immune response and stimulate high levels of neutralising antibodies.

Efficacy

According to New England Journal of medicine
Novavax is 90.4% effective in preventing symptomatic covid 19. The vaccine is 100% effective in preventing moderate to severe covid 19.

Side effects

More Common after second dose and fewer than Pfizer and moderna

Tenderness at the site of injection
Pain upon and after vaccination
Fatigue
Muscle pain
Headache
Malaise

Less common symptoms include a fever, nausea and vomiting, joint pain

Who should get novavax?

1. Individuals with Any chronic conditions that increase the risk of severe COVID-19 such as cardiovascular disease, respiratory disease and diabetes
2. People who have contracted COVID-19 in the past
3. People who are breast feeding and those who are not

Do NOT get the vaccine

1. People with history of anaphylaxis to any component inside the vacvjne
2. People with symptomatic pcr confirmed COVID-19 until they have recovered and finished isolation
3. People with body temperature over 38.5 degree celcius until they no longer have a fever
4. People who are under 18, as research studying its safety and efficacy is still underway

Reference: Medical News Today

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