BA.4 / BA.5 | Omicron | 4 Times More Resistant To mRNA Vaccines 🔎🔍
🎞️ · 29.07.2022 · 00:11:40 ··· Freitag ⭐ 0 🎬 0
📺Vithal Panday, M.D.
🎬 · 29.07.2022 · 00:11:40 ··· Freitag
😎 · 03.07.2024 · 15:40:29 ··· MiTTwoch
BA. 4 and BA. 5 are currently the dominant strains of new covid causes, accounting for over 80% of cases in US. These two subvariants are over 4 times more resistant to antibodies in individuals who received messenger RNA vaccines.
These subvariants likely evolved from the previously dominant BA. 2 Omicron Variant.
Today we will discuss
1. Background
2. How omicron subvariants affect hospitalisation rates
3. Spike protein mutations
4. Variants of concern
5. Symptoms
6. How can you treat a mild infection
Background
BA. 4 and BA. 5 were initially found in South Africa in April 2022 and spread rapidly across the globe. These subvariants have a high transmission rate. They carry mutations on their spike protein, which is the part of the virus that attavhes to ACE2 receptors on human cells so they can enter them.
Even though new research shows that immunity against the dominant omicron subvariants appears to be waning, we should note that MRNA vaccines continue to provide B and T cell based protection against severe outcomes from covid - hospitalisation and death.
How omicron subvariants affect hospitalisation rates?
Each country will have their own immune profiles again covid. This is due to vaccination rates, circulating strains and general risk profiles (age, public safety measures))
Portugal has a more significant effect from BA. 4 and BA. 5 even though they have a high vaccination rate. This is because they have an older population.
BA. 4 and BA. 5 may lead to increased hospitalizations particularly amongst unvaccjnaged, the immunosuppressed and those of advanced age. Vaccination is important because although there is an increase in cases, there are fewer hospitalizations because of the impact of immunity.
Spike protein mutations
Both subvariants are similar to omicron BA. 2 which is currently dominant in the United Kingdom, continental Europe and the US.
BA. 4 and BA. 5 have identical mutations on their spike protein which is the part of the virus that attavhes to receptors on humans cells. This differentiates these subvariants from BA. 2. Each Subvariant has its own mutation in other areas of the virus.
Variants of concern
BA. 4 and BA. 5 are variants of concern because they are more transmissible and are the cause of the recent spikes in positive cases. Let's not forget that these subvariants can easily evade our immune system.
Vaccines don't prevent disease - vaccination prevents disease. The issue is whether or not everyone can be persuaded to be vaccinated, yet again.
Symptoms
The most commonly reported symptoms were a runny nose, headache, fatigue, sneezing and a sore throat. Other symptoms include a fever or chills, shortness of breath or difficulty breathing, new loss of taste or smell, nausea or vomiting and diarrhea.
Note that this list is not exhaustive and people might experience different symptoms or combinations of symptoms.
How can you treat a mild infection?
Reccomended treatment is directed at the symptoms: stay hydrated, rested and well nourished. Take acetaminophen or ibuprofen to relieve headaches, body aches or fever. Avoid unproven remedies like hydroxy chloroquine, ivermectin, zinc and vitamin D which have no known value and can cause adverse effects.
Reference: Medical News Today
SELECT * FROM DAvidON WHERE `DAvid`="CkJWWPtTZ-o" ORDER BY ts
SELECT * FROM DAvidPlay WHERE `DAvid`="CkJWWPtTZ-o"
***
· 29.07.2022 · 00:11:40 ··· Freitag
U
U
L
L
T
* 1659046300
* 1659046300
X 0
Y 0
P
C 17882
B 8
V 36
* · 23.07.2022 · 00:00:00 ···
2 · 25.07.2023 · 22:54:24 ···
L · 27.07.2024 · 23:16:45 ···
C · 27.07.2024 · 23:16:46 ···
💘 🖱️ * · 01.01.1970 · 01:00:00 ···
* · 01.01.1970 · 01:00:00 ···
· 01.01.1970 · 01:00:00 ···
**##
*** · 01.01.1970 · 01:00:00 ··· ::
*2* · 01.01.1970 · 01:00:00 ··· ::
*L* · 01.01.1970 · 01:00:00 ··· ::
*C* · 01.01.1970 · 01:00:00 ··· ::
********
